28 February 2020
Vol 367, Issue 6481

About The Cover

Cover image expansion

COVER CRISPR-Cas9 technology acts as molecular scissors to edit DNA. Genetically modified T cells are revolutionizing cancer therapy but do not successfully treat all patients. Researchers used CRISPR to cut out sections of DNA on three genes in T cells from patients with advanced cancer. This pioneering therapeutic application of genome editing paves the way for next-generation cell-based therapies for human disease. See pages 976 and eaba7365.
Illustration: V. Altounian/Science