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How I faced my coronavirus anxiety

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Science  20 Mar 2020:
Vol. 367, Issue 6484, pp. 1398
DOI: 10.1126/science.367.6484.1398

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  • RE: How I faced my coronavirus anxiety--our synergistic prophylactic proposal
    • Jyotsna Nair, Physician, Director of Psychiatric Services, Change Academy, Lake of the Ozarks
    • Other Contributors:
      • Sachin Nair, Helper, Change Academy, Lake of the Ozarks
      • Nihaal Nath, student, University of Missouri
      • Rattan Nath, scientist, retired

    We dealt with our anxieties by trying to devise safer strategies to buy time for all of us on the frontlines. Covid-19 presents a balancing act when it comes to prophylaxis.
    Covid-19 poses an unprecedented challenge to both public health and the world economy--presently a recession is widely expected. Covid-19 is both very infectious and lethal to the elderly and the front line workers taking care of the infected (1). The response to Covid-19 has ranged from secrecy (hoping it would just go away) to aggressive actions to ‘flatten the curve’ (2). It is reasonable to expect more such influenza-like viruses that target the lungs resulting in Acute Respiratory Distress Syndrome (ARDS) as human activity and commerce grow. Covid-19 has already resulted in a mounting death toll and exhaustion of resources.
    Covid-19, like other influenza-like infections, is progressively more lethal to those above the age of 20 years with a reasonably prompt recovery from the infection--there are few deaths below the age of 20 years (3) without other comorbidities like immunosuppression. At about age of 20, humans complete the changes due to puberty with Human Growth Hormones (HGH) levels falling from that age onward. Autocrine HGH has a role in lung development/maintenance (4), which are deficient in lethal ARDS (5). Recombinant HGH (rHGH) is commercially available. Experience with rHGH shows that it (i) helps with weight gain and improve lung function after lung reduction surgery (6)...

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    Competing Interests: None declared.

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