Contents
08 May 2020
Vol 368, Issue 6491
Vol 368, Issue 6491
Special Issue
Early Life Immunology
Introduction to special issue
Reviews
Contents
This Week in Science
Editorial
Editors' Choice
Products & Materials
- New Products
A weekly roundup of information on newly offered instrumentation, apparatus, and laboratory materials of potential interest to researchers.
In Brief
In Depth
- NIH move to ax bat coronavirus grant draws fire
Controversy comes amid global calls for China to allow independent probe of virus origins.
- Children's role in pandemic is still a puzzle
Some countries reopen schools, hoping it won't accelerate transmission.
- The race is on for antibodies that stop the new coronavirus
Mass-produced immune proteins may outpace a vaccine.
- Ape researchers mobilize to save primates from coronavirus
Past respiratory epidemics raise fears of infection in apes.
- Without fossil fuels, reactors churn out chemicals
Prospects brighten for making fertilizer, plastics with solar and wind power.
- Paperwork mistakes ensnare health data expert
Georgia Tech professor faces sentencing—and may lose her job—for mishandling grant.
Feature
- Meet the psychobiome
Mounting evidence that gut bacteria influence the nervous system inspires efforts to mine the microbiome for brain drugs.
Working Life
Letters
Books et al.
- A field guide to existential risk
A pandemic isn't the only peril for which we're unprepared
- The secret lives of birds
A science writer weaves a vivid portrait of avian culture, communication, and care
Policy Forum
- In pursuit of open science, open access is not enough
Preventing monopolies in knowledge infrastructure is the next battleground for publishers and research institutions
- Harnessing multiple models for outbreak management
Expert elicitation methods and a structured decision-making framework will help account for risk and uncertainty
Perspectives
- Tree planting is not a simple solution
Tree planting must be carefully planned and implemented to achieve desired outcomes
- Quantum resonances near absolute zero
Ultralow-energy atom-molecule collisions reveal quasi-bound state quantum resonances
- Closing the science gap in 3D metal printing
X-ray imaging and modeling reveal how metal powders absorb energy and can create defects
- Sending copper where it is needed most
Elesclomol improves survival in a mouse model of Menkes disease
- Drones become even more insect-like
Mosquitoes' exceptional sensitivity to sound and airflow inspires new collision avoidance technology
- Toward artificial photosynthesis
Microfluidics lights the way to a synthetic plant-like cell
- The challenge of early detection in cancer
Tumor growth dynamics and the timing of metastasis impose limits on cancer screening
Research Articles
- Quantifying SARS-CoV-2 transmission suggests epidemic control with digital contact tracing
Instantaneous contact tracing and notifications by mobile phone app could potentially stop the COVID-19 epidemic.
- Elesclomol alleviates Menkes pathology and mortality by escorting Cu to cuproenzymes in mice
Elesclomol therapy stops the progression of neurodegeneration and improves survival in a mouse model of Menkes disease.
Reports
- Imaging the onset of the resonance regime in low-energy NO-He collisions
Inelastic NO-He scattering is probed in the ultracold regime with high precision and resonance resolution.
- A highly conserved cryptic epitope in the receptor binding domains of SARS-CoV-2 and SARS-CoV
Structural studies show that a SARS antibody binds a conserved epitope on the viral spike distinct from the receptor-binding site.
- Aerodynamic imaging by mosquitoes inspires a surface detector for autonomous flying vehicles
Low-power sensing of flow fields by mosquitoes can inspire collision avoidance devices.
- An investigation of transmission control measures during the first 50 days of the COVID-19 epidemic in China
Travel restrictions and the national emergency response delayed the growth and limited the size of the COVID-19 epidemic in China.
- Emergence of complexity in hierarchically organized chiral particles
Chiral colloidal particles with complex surface morphologies were assembled from polydisperse gold-cysteine nanoplatelets.
- Light-powered CO2 fixation in a chloroplast mimic with natural and synthetic parts
Natural photosynthetic components power a synthetic CO2 fixation pathway in picoliter droplets.
- Sample collection from asteroid (162173) Ryugu by Hayabusa2: Implications for surface evolution
A sample of the nearby asteroid Ryugu, collected by Hayabusa2, should arrive on Earth in December 2020.
- Controlling interdependent meso-nanosecond dynamics and defect generation in metal 3D printing
Multiscale physics models help isolate a stability criterion that is useful for avoiding defects in laser bed powder fusion printing.
- Intermolecular vibrational energy transfer enabled by microcavity strong light–matter coupling
Strong light–matter coupling enables selective intermolecular vibrational energy transfer in the liquid phase.
Technical Comments
Errata
About The Cover
COVER Illustrated mosaic of a mother with child, assembled from various immune cell types. The developing immune system interacts with and is influenced by several factors, including the mother's cells (and her commensal microbiota) in utero and after birth. This special issue celebrates recent advances in early life immunology, which will help inform strategies to combat both childhood infections and immune disorders in later life. See page 598.
Illustration: Charis Tsevis
