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Architecture and function of human uromodulin filaments in urinary tract infections

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Science  21 Aug 2020:
Vol. 369, Issue 6506, pp. 1005-1010
DOI: 10.1126/science.aaz9866

Article Information

vol. 369 no. 6506 1005-1010

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History: 
  • Received for publication October 25, 2019
  • Resubmitted April 22, 2020
  • Accepted for publication June 18, 2020
  • .

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Author Information

  1. Gregor L. Weiss1,*,
  2. Jessica J. Stanisich1,*,
  3. Maximilian M. Sauer1,*,,
  4. Chia-Wei Lin2,,
  5. Jonathan Eras1,
  6. Dawid S. Zyla1,
  7. Johannes Trück3,
  8. Olivier Devuyst4,5,
  9. Markus Aebi2,
  10. Martin Pilhofer1,§,
  11. Rudi Glockshuber1
  1. 1Institute of Molecular Biology and Biophysics, ETH Zürich, Otto-Stern-Weg 5, CH-8093 Zürich, Switzerland.
  2. 2Institute of Microbiology, ETH Zürich, Vladimir-Prelog-Weg 1-5/10, CH-8093 Zürich, Switzerland.
  3. 3University Children’s Hospital Zürich, Steinwiesstrasse 75, CH-8032 Zürich, Switzerland.
  4. 4Institute of Physiology, Mechanisms of Inherited Kidney Disorders, University of Zürich, Winterthurerstrasse 190, CH-8057 Zürich, Switzerland.
  5. 5Division of Nephrology, UCLouvain Medical School, Brussels, Belgium.
  1. §Corresponding author. Email: pilhofer{at}biol.ethz.ch
  1. * These authors contributed equally to this work.

  • Present address: Department of Biochemistry, University of Washington, 1705 NE Pacific St., Seattle, WA 98195, USA.

  • Present address: Functional Genomics Center Zürich, Winterthurerstrasse 190, CH-8057 Zürich, Switzerland.

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