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A molecular pore spans the double membrane of the coronavirus replication organelle

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Science  11 Sep 2020:
Vol. 369, Issue 6509, pp. 1395-1398
DOI: 10.1126/science.abd3629

Article Information

vol. 369 no. 6509 1395-1398

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History: 
  • Received for publication June 22, 2020
  • Accepted for publication July 31, 2020
  • .

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Author Information

  1. Georg Wolff1,
  2. Ronald W. A. L. Limpens1,
  3. Jessika C. Zevenhoven-Dobbe2,
  4. Ulrike Laugks3,
  5. Shawn Zheng4,
  6. Anja W. M. de Jong1,
  7. Roman I. Koning1,
  8. David A. Agard5,
  9. Kay Grünewald3,6,
  10. Abraham J. Koster1,
  11. Eric J. Snijder2,
  12. Montserrat Bárcena1,*
  1. 1Section Electron Microscopy, Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden 2333 ZC, Netherlands.
  2. 2Molecular Virology Laboratory, Department of Medical Microbiology, Leiden University Medical Center, Leiden 2333 ZA, Netherlands.
  3. 3Department of Structural Cell Biology of Viruses, Centre for Structural Systems Biology, Heinrich Pette Institute, Leibnitz Institute of Experimental Virology, 22607 Hamburg, Germany.
  4. 4Howard Hughes Medical Institute, Department of Biochemistry and Biophysics, University of California San Francisco, San Francisco, CA 94143, USA.
  5. 5Department of Biochemistry and Biophysics, University of California San Francisco, San Francisco, CA 94143, USA.
  6. 6Department of Chemistry, MIN Faculty, Universität Hamburg, 20146 Hamburg, Germany.
  1. *Corresponding author. Email: m.barcena{at}lumc.nl

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