Research Article

Species-specific segmentation clock periods are due to differential biochemical reaction speeds

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Science  18 Sep 2020:
Vol. 369, Issue 6510, pp. 1450-1455
DOI: 10.1126/science.aba7668

Article Information

vol. 369 no. 6510 1450-1455

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History: 
  • Received for publication January 3, 2020
  • Accepted for publication July 17, 2020
  • .

Author Information

  1. Mitsuhiro Matsuda1,2,
  2. Hanako Hayashi1,*,
  3. Jordi Garcia-Ojalvo3,
  4. Kumiko Yoshioka-Kobayashi4,,
  5. Ryoichiro Kageyama4,5,
  6. Yoshihiro Yamanaka6,7,
  7. Makoto Ikeya6,
  8. Junya Toguchida4,6,
  9. Cantas Alev6,7,
  10. Miki Ebisuya1,2,
  1. 1RIKEN Center for Biosystems Dynamics Research (RIKEN BDR), 2-2-3 Minatojima-minamimachi, Chuo-ku, 650-0047 Kobe, Japan.
  2. 2European Molecular Biology Laboratory (EMBL) Barcelona, Dr. Aiguader 88, 08003 Barcelona, Spain.
  3. 3Department of Experimental and Health Sciences, Universitat Pompeu Fabra, Dr. Aiguader 88, 08003 Barcelona, Spain.
  4. 4Institute for Frontier Life and Medical Sciences, Kyoto University, Shogoin-Kawahara-cho, Sakyo-ku, 606-8507 Kyoto, Japan.
  5. 5Institute for Integrated Cell-Material Sciences, Kyoto University, Yoshida Ushinomiya-cho, Sakyo-ku, 606-8501 Kyoto, Japan.
  6. 6Center for iPS Cell Research and Application (CiRA), Kyoto University, 53 Shogoin-Kawahara-cho, Sakyo-ku, 606-8507 Kyoto, Japan.
  7. 7Institute for the Advanced Study of Human Biology (ASHBi), Kyoto University, Yoshida-Konoe-cho, Sakyo-ku, 606-8501 Kyoto, Japan.
  1. Corresponding author. Email: miki.ebisuya{at}embl.es
  • * Present address: Department of Biochemistry, University of Oxford, Oxford OX1 3QU, UK.

  • Present address: Institute for the Advanced Study of Human Biology (ASHBi), Kyoto University, Yoshida-Konoe-cho, Sakyo-ku, 606-8501 Kyoto, Japan.

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