09 October 2020
Vol 370, Issue 6513

About The Cover

Cover image expansion

COVER The spike protein (teal), covered in protective glycan molecules, on the surface of SARS-CoV-2 is the primary target for COVID-19 vaccine development. The spike contains three hinges that enable it to be highly flexible on the viral surface and may facilitate host cell entry. The spike positions shown here are from structural data of intact SARS-CoV-2 virions. See page 203. Illustration: V. Altounian/Science; Data: Paul Ehrlich Institute, European Molecular Biology Laboratory, and Max Planck Institute of Biophysics