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Neuropilin-1 is a host factor for SARS-CoV-2 infection
- View ORCID ProfileJames L. Daly1,*,
- View ORCID ProfileBoris Simonetti1,*,†,
- View ORCID ProfileKatja Klein2,*,
- View ORCID ProfileKai-En Chen3,‡,
- View ORCID ProfileMaia Kavanagh Williamson2,‡,
- View ORCID ProfileCarlos Antón-Plágaro1,‡,
- View ORCID ProfileDeborah K. Shoemark4,
- Lorena Simón-Gracia5,
- View ORCID ProfileMichael Bauer6,
- Reka Hollandi7,
- View ORCID ProfileUrs F. Greber6,
- Peter Horvath7,8,
- View ORCID ProfileRichard B. Sessions1,
- Ari Helenius9,
- View ORCID ProfileJulian A. Hiscox10,11,
- View ORCID ProfileTambet Teesalu5,
- View ORCID ProfileDavid A. Matthews2,
- View ORCID ProfileAndrew D. Davidson2,
- View ORCID ProfileBrett M. Collins3,
- View ORCID ProfilePeter J. Cullen1,†,
- View ORCID ProfileYohei Yamauchi2,12,†
- 1School of Biochemistry, Faculty of Life Sciences, Biomedical Sciences Building, University of Bristol, Bristol BS8 1TD, UK.
- 2School of Cellular and Molecular Medicine, Faculty of Life Sciences, Biomedical Sciences Building, University of Bristol, Bristol BS8 1TD, UK.
- 3Institute for Molecular Bioscience, the University of Queensland, St. Lucia, QLD 4072, Australia.
- 4School of Biochemistry and BrisSynBio Centre, Faculty of Life Sciences, Biomedical Sciences Building, University of Bristol, Bristol BS8 1TD, UK.
- 5Laboratory of Cancer Biology, Institute of Biomedicine and Translational Medicine, University of Tartu, Tartu, Estonia.
- 6Department of Molecular Life Sciences, University of Zurich, Winterthurerstrasse 190, 8057 Zürich, Switzerland.
- 7Synthetic and Systems Biology Unit, Biological Research Centre (BRC), Szeged, Hungary.
- 8Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland.
- 9Institute of Biochemistry, ETH Zurich, Zurich, Switzerland.
- 10Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, UK.
- 11Singapore Immunology Network, Agency for Science, Technology, and Research, 138648, Singapore.
- 12Division of Biological Science, Graduate School of Science, Nagoya University, Furo-cho, Chikusa-ku, Nagoya, 464-8601, Japan.
- ↵†Corresponding author. Email: bs13866{at}bristol.ac.uk (B.S.); pete.cullen{at}bristol.ac.uk (P.J.C.); yohei.yamauchi{at}bristol.ac.uk (Y.Y.)
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Science 13 Nov 2020:
Vol. 370, Issue 6518, pp. 861-865
DOI: 10.1126/science.abd3072
Vol. 370, Issue 6518, pp. 861-865
DOI: 10.1126/science.abd3072
James L. Daly
1School of Biochemistry, Faculty of Life Sciences, Biomedical Sciences Building, University of Bristol, Bristol BS8 1TD, UK.
Boris Simonetti
1School of Biochemistry, Faculty of Life Sciences, Biomedical Sciences Building, University of Bristol, Bristol BS8 1TD, UK.
Katja Klein
2School of Cellular and Molecular Medicine, Faculty of Life Sciences, Biomedical Sciences Building, University of Bristol, Bristol BS8 1TD, UK.
Kai-En Chen
3Institute for Molecular Bioscience, the University of Queensland, St. Lucia, QLD 4072, Australia.
Maia Kavanagh Williamson
2School of Cellular and Molecular Medicine, Faculty of Life Sciences, Biomedical Sciences Building, University of Bristol, Bristol BS8 1TD, UK.
Carlos Antón-Plágaro
1School of Biochemistry, Faculty of Life Sciences, Biomedical Sciences Building, University of Bristol, Bristol BS8 1TD, UK.
Deborah K. Shoemark
4School of Biochemistry and BrisSynBio Centre, Faculty of Life Sciences, Biomedical Sciences Building, University of Bristol, Bristol BS8 1TD, UK.
Lorena Simón-Gracia
5Laboratory of Cancer Biology, Institute of Biomedicine and Translational Medicine, University of Tartu, Tartu, Estonia.
Michael Bauer
6Department of Molecular Life Sciences, University of Zurich, Winterthurerstrasse 190, 8057 Zürich, Switzerland.
Reka Hollandi
7Synthetic and Systems Biology Unit, Biological Research Centre (BRC), Szeged, Hungary.
Urs F. Greber
6Department of Molecular Life Sciences, University of Zurich, Winterthurerstrasse 190, 8057 Zürich, Switzerland.
Peter Horvath
7Synthetic and Systems Biology Unit, Biological Research Centre (BRC), Szeged, Hungary.
8Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland.
Richard B. Sessions
1School of Biochemistry, Faculty of Life Sciences, Biomedical Sciences Building, University of Bristol, Bristol BS8 1TD, UK.
Ari Helenius
9Institute of Biochemistry, ETH Zurich, Zurich, Switzerland.
Julian A. Hiscox
10Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, UK.
11Singapore Immunology Network, Agency for Science, Technology, and Research, 138648, Singapore.
Tambet Teesalu
5Laboratory of Cancer Biology, Institute of Biomedicine and Translational Medicine, University of Tartu, Tartu, Estonia.
David A. Matthews
2School of Cellular and Molecular Medicine, Faculty of Life Sciences, Biomedical Sciences Building, University of Bristol, Bristol BS8 1TD, UK.
Andrew D. Davidson
2School of Cellular and Molecular Medicine, Faculty of Life Sciences, Biomedical Sciences Building, University of Bristol, Bristol BS8 1TD, UK.
Brett M. Collins
3Institute for Molecular Bioscience, the University of Queensland, St. Lucia, QLD 4072, Australia.
Peter J. Cullen
1School of Biochemistry, Faculty of Life Sciences, Biomedical Sciences Building, University of Bristol, Bristol BS8 1TD, UK.
Yohei Yamauchi
2School of Cellular and Molecular Medicine, Faculty of Life Sciences, Biomedical Sciences Building, University of Bristol, Bristol BS8 1TD, UK.
12Division of Biological Science, Graduate School of Science, Nagoya University, Furo-cho, Chikusa-ku, Nagoya, 464-8601, Japan.
