In DepthCOVID-19

People with Down syndrome face high risk from coronavirus

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Science  18 Dec 2020:
Vol. 370, Issue 6523, pp. 1384-1385
DOI: 10.1126/science.370.6523.1384

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  • RE: Covid-19, Down's Syndrome, and DHEA

    It is my hypothesis that Down's syndrome and Covid-19 infection and subsequent pathology are both caused by low dehydroepiandrosterone (DHEA). DHEA has already been demonstrated to protect against other viruses: "In this study it was shown that DHEA protects mice against WNV, SVNI and SFV lethal infection." (
    Arch Virol. 1991;120(3-4):263-71. doi: 10.1007/BF01310481.) I have submitted explanations of low DHEA regarding Covid-19 infection and Down's syndrome to numerous researchers and received no response. It is disconcerting that a possible basis of treatment of these may be treated with DHEA is being ignored.

    Competing Interests: None declared.

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