Contents
26 March 2021
Vol 371, Issue 6536
Vol 371, Issue 6536
Contents
This Week in Science
Editorial
Editors' Choice
Products & Materials
- New Products
A weekly roundup of information on newly offered instrumentation, apparatus, and laboratory materials of potential interest to researchers.
In Brief
In Depth
- New problems erode confidence in AstraZeneca's vaccine
Rare clotting disorders interrupt vaccination in Europe as U.S. expert panel rebukes company over efficacy data
- Remains of Moon-forming impact may lie deep in Earth
Mysterious rocks at mantle's base tied to violent “Theia” strike 4.5 billion years ago
- Deadly viral outbreak ravages European horses
Researchers are studying why a common herpesvirus suddenly took a serious toll
- Mysterious eagle killer identified
A new species of cyanobacteria that lives on invasive waterweed produces an unusual neurotoxin
- Great Lakes people among first coppersmiths
New dates show Native Americans worked pure ore nearly 10,000 years ago
- Carbon capture marches toward practical use
New CO2-grabbing materials and policies could cut emissions from fossil fuel plants
- Lens array captures dim objects missed by giant telescopes
Upgraded Dragonfly will study how dark matter shapes diffuse galaxies and faint tendrils of gas
Feature
- Long live the queen
In insect societies, a queen can live for years, whereas workers expire in months. What can hives and anthills reveal about aging?
Working Life
Letters
Books et al.
- The conservationists
Passionate advocates have helped humanity rethink its relationship with Earth's other species
- A planet remade in our image
As Anthropocene impacts accumulate, a sometimes-unrecognizable Earth emerges
Policy Forum
- Raising standards to lower diesel emissions
California policies protect vulnerable communities the most and should be adopted nationwide
Perspectives
- The emerging plasticity of SARS-CoV-2
The evolution of SARS-CoV-2 poses challenges for vaccines and immunotherapies
- Unusual T cell receptor in opossum
The structure of a marsupial T cell receptor illustrates the emerging trend of noncanonical antigen binding
- Catching the wave
Uncoupling metabolism from cytoskeletal regulation leads to T cell dysfunction
- Gold meets peptides in a hybrid coil
Twisted structures are assembled cooperatively by β-sheet peptides and gold nanorods
- At the beginning of speciation
Appearance and song are sexually selected factors to maintain a new bird species
- Getting excited about cycloadditions
Photoactivation to long-lived triplet excited states enables cycloadditions with heteroarenes
Association Affairs
- Scientific excellence and diversity at Annual Meeting
Showcasing diverse speakers requires a deliberate commitment to inclusion from decision-makers
Research Articles
- Rapid speciation via the evolution of pre-mating isolation in the Iberá Seedeater
Females’ choices have driven assortative mating and speciation in capuchino seedeater birds in a national park in Argentina.
- Liver type 1 innate lymphoid cells develop locally via an interferon-γ–dependent loop
Innate lymphoid cells in the liver produce IFN-γ, which promotes development of local innate lymphoid cell progenitors.
- WAVE2 suppresses mTOR activation to maintain T cell homeostasis and prevent autoimmunity
Cytoskeletal regulatory WAVE2 protein plays a critical role in the regulation of T cell quiescence and immune homeostasis.
- Photoinduced receptor confinement drives ligand-independent GPCR signaling
Laser control of receptor clustering enables studies of cell signaling.
- Age groups that sustain resurging COVID-19 epidemics in the United States
More targeted interventions in the 20-to-49 age group could bring epidemic waves under control and facilitate the safe reopening of schools.
- Hunting the eagle killer: A cyanobacterial neurotoxin causes vacuolar myelinopathy
A deadly toxin that kills bald eagles originated from an environmental interaction between an invasive plant, a cyanobacterium, and bromide.
- Photochemical intermolecular dearomative cycloaddition of bicyclic azaarenes with alkenes
A photoexcited triplet sensitizer enables otherwise unfavorable cycloaddition reactivity of heteroaromatic compounds.
- A 35-million-year record of seawater stable Sr isotopes reveals a fluctuating global carbon cycle
Measurements of 88Sr and 86Sr in marine barite help reveal past carbon cycle variability.
- Molecular mechanism of cytokinin-activated cell division in Arabidopsis
The plant hormone cytokinin triggers a self-amplifying loop that drives cell proliferation and meristem growth.
Review
Reports
- Controlling quantum many-body dynamics in driven Rydberg atom arrays
Periodic driving of a Rydberg atom array is used to demonstrate control of quantum many-body dynamics.
- Stabilizing black-phase formamidinium perovskite formation at room temperature and high humidity
Vertically aligned lead iodide thin films grown from an ionic liquid enable ambient growth of black-phase perovskite.
- Three-dimensional vectorial imaging of surface phonon polaritons
Electron microscopy provides a map of the phonon-polariton excitations of 3D nanostructures.
- Enhanced optical asymmetry in supramolecular chiroplasmonic assemblies with long-range order
Assembly of gold nanorods with amyloid polypeptides amplifies their chiral g-factors to levels comparable to those of liquid crystals.
- SARS-CoV-2 Mpro inhibitors with antiviral activity in a transgenic mouse model
Designed SARS-CoV-2 Mpro (main protease) inhibitors display excellent antiviral activity both in vitro and in a transgenic mouse model.
- Intranasal fusion inhibitory lipopeptide prevents direct-contact SARS-CoV-2 transmission in ferrets
A dimeric form of a SARS-CoV-2–derived lipopeptide is a potent inhibitor of fusion and infection in vitro and transmission in vivo.
- The molecular assembly of the marsupial γμ T cell receptor defines a third T cell lineage
T cells that use a γµ T cell receptor define a third lineage found exclusively in the gray short-tailed opossum and other non-eutherian mammals.
From the AAAS Office of Publishing
Technical Comments
Erratum
About The Cover
COVER A bald eagle (Haliaeetus leucocephalus) clutches a shad as it flies over the White River in Arkansas. Bald eagles and other wildlife can succumb to vacuolar myelinopathy, a neurological disease. A cyanobacterium that grows on invasive aquatic plants produces the disease-causing neurotoxin, affecting wildlife in a bottom-up trophic cascade through the food chain. Toxin biosynthesis relies on bromide, so monitoring and management of the plant host, bromide levels, and neurotoxin are critical for protecting wildlife and human health. See pages 1298 and eaax9050.
Photo: Mike Martin
