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A third purine biosynthetic pathway encoded by aminoadenine-based viral DNA genomes

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Science  30 Apr 2021:
Vol. 372, Issue 6541, pp. 516-520
DOI: 10.1126/science.abe6494

Article Information

vol. 372 no. 6541 516-520

PubMed: 
Print ISSN: 
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History: 
  • Received for publication September 4, 2020
  • Accepted for publication March 25, 2021
  • .

Author Information

  1. Dona Sleiman1,,
  2. Pierre Simon Garcia2,3,,
  3. Marion Lagune1,
  4. Jerome Loc’h4,
  5. Ahmed Haouz5,
  6. Najwa Taib2,6,
  7. Pascal Röthlisberger7,
  8. Simonetta Gribaldo2,
  9. Philippe Marlière8,
  10. Pierre Alexandre Kaminski1,*
  1. 1Biology of Gram-Positive Pathogens, Institut Pasteur, CNRS-UMR 2001, Paris, France.
  2. 2Evolutionary Biology of the Microbial Cell, Institut Pasteur, CNRS-UMR 2001, Paris, France.
  3. 3Stress Adaptation and Metabolism, Institut Pasteur, CNRS-UMR 2001, Paris, France.
  4. 4Structural Dynamics of Macromolecules, Institut Pasteur, CNRS-UMR 3528, Paris, France.
  5. 5Crystallography Platform, C2RT, Institut Pasteur, CNRS-UMR 3528, Paris, France.
  6. 6Hub Bioinformatics and Biostatistics, Institut Pasteur, Paris, France.
  7. 7Bioorganic Chemistry of Nucleic Acids, Institut Pasteur, CNRS-UMR 3523, Paris, France.
  8. 8Génomique Métabolique, Genoscope, Institut François Jacob, CEA, CNRS, Université Evry, Université Paris-Saclay, Evry, France.
  1. *Corresponding author. Email: pierre-alexandre.kaminski{at}pasteur.fr
  1. These authors contributed equally to this work.

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