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Mitochondrial NADP(H) generation is essential for proline biosynthesis

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Science  28 May 2021:
Vol. 372, Issue 6545, pp. 968-972
DOI: 10.1126/science.abd5491

Article Information

vol. 372 no. 6545 968-972

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History: 
  • Received for publication June 27, 2020
  • Accepted for publication April 7, 2021
  • .

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Author Information

  1. Jiajun Zhu1,
  2. Simon Schwörer1,,
  3. Mirela Berisa2,,
  4. Yeon Ju Kyung1,,
  5. Keun Woo Ryu1,
  6. Junmei Yi3,
  7. Xuejun Jiang3,
  8. Justin R. Cross2,
  9. Craig B. Thompson1,*
  1. 1Department of Cancer Biology and Genetics, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  2. 2The Donald B. and Catherine C. Marron Cancer Metabolism Center, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  3. 3Cell Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  1. *Corresponding author. Email: thompsonc{at}mskcc.org
  1. These authors contributed equally to this work.

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