Contents
23 July 2021
Vol 373, Issue 6553
Vol 373, Issue 6553
Contents
This Week in Science
Editorial
Editors' Choice
In Brief
In Depth
- Europe's deadly floods leave scientists stunned
Despite improvements, flood forecasts sometimes failed to flag risks along smaller streams.
- Alzheimer's drug approval spotlights blood tests
Physicians hope technology will help screen patients eligible for Biogen's controversial antibody, aducanumab.
- A few lucky researchers return to the field
The pandemic has transformed fieldwork and upended careers.
- DNA plucked from air identifies nearby animals
Analysis of airborne cells could survey biodiversity, two studies of zoo animals suggest.
- Event Horizon Telescope images second black hole's jets
Globe-spanning instrument's snapshot of Centaurus A galaxy suggests all black holes operate similarly.
- WHO chief pressures China on pandemic origin
Agency director calls for lab audits and more studies of how SARS-CoV-2 emerged.
Feature
- A troubled calculus
Researchers use race to build disease risk assessment tools. Can removing it help resolve medicine's race crisis?
Working Life
Letters
Books et al.
- The elusive quest to make consistent calls
Variability in high-stakes decision-making is more prevalent than we might like to believe
- An atomic warning
Early efforts to expand nuclear energy were rife with racism and peril, reminds a historian
Policy Forum
- Global implications of the EU battery regulation
A much-needed law may have unintended global consequences
Perspectives
- The interior of Mars revealed
Direct seismic observations provide clues to the red planet's structure and evolution
- Coherent manipulation of a spin qubit
A new device opens new avenues for spin qubits
- The inner workings of an enzyme
A high-throughput mutation screen dissects the mechanistic basis of enzyme activity
- Proximity and single-molecule energetics
Scanning probes measure how nearby oxygen molecules affect triplet lifetimes of pentacene
- Experimental jurisprudence
Psychologists probe lay understandings of legal constructs
- Bespoke brain immunity
The brain and spinal cord maintain a distinct cache of immune cells
- Scent of a vaccine
Intranasal vaccination should block SARS-CoV-2 transmission at the source
- Ei-ichi Negishi (1935–2021)
Pioneering chemist who used transition metals to make and break bonds
Research Articles
- Retinal waves prime visual motion detection by simulating future optic flow
Spontaneous retinal activity during development guides refinement of brain circuits that interpret movement through space.
- Enterically derived high-density lipoprotein restrains liver injury through the portal vein
High-density lipoprotein from the ileum shields the liver from inflammation and fibrosis.
- Skull and vertebral bone marrow are myeloid cell reservoirs for the meninges and CNS parenchyma
Bone marrow niches adjacent to the brain and spinal cord supply B cells and myeloid cells to the meninges and central nervous system.
- Revealing enzyme functional architecture via high-throughput microfluidic enzyme kinetics
A microfluidic platform for high-throughput quantitative biochemistry reveals enzyme architectures that shape function.
- Heterogeneity of meningeal B cells reveals a lymphopoietic niche at the CNS borders
Bone marrow niches adjacent to the brain and spinal cord supply B cells and myeloid cells to the meninges and central nervous system.
- Structure of an AMPK complex in an inactive, ATP-bound state
Conformation-specific antibodies trap adenosine monophosphate–activated protein kinase in a fully inactive state.
- Plant “helper” immune receptors are Ca2+-permeable nonselective cation channels
Calcium signaling across the cell membrane links pathogen infection to programmed cell death in plants.
- Peta–electron volt gamma-ray emission from the Crab Nebula
Detection of the Crab Nebula at peta–electron volt energies constrains the gamma-ray emission mechanism.
Reports
- Coherent manipulation of an Andreev spin qubit
The electronic excitations of low-temperature superconductors are used to realize a superconducting spin qubit.
- Upper mantle structure of Mars from InSight seismic data
Data from the InSight mission on Mars help constrain the structure and properties of the martian interior.
- Thickness and structure of the martian crust from InSight seismic data
Data from the InSight mission on Mars help constrain the structure and properties of the martian mantle.
- Seismic detection of the martian core
Data from the InSight mission on Mars help constrain the structure and properties of the martian interior.
- Inhibited nonradiative decay at all exciton densities in monolayer semiconductors
Mechanical strain shifts van Hove resonances and circumvents exciton-exciton annihilation at high photocarrier densities.
- Atomically resolved single-molecule triplet quenching
Single-molecule triplet states and their interactions with O2 molecules can be tracked with real-space atomic resolution.
- Innovation and geographic spread of a complex foraging culture in an urban parrot
Bin opening by urban sulphur-crested cockatoos reveals cultural complexity in parrots.
About The Cover
COVER Vital clues to a planet's geologic history are contained in its interior. For 2 years on Mars, the InSight lander has recorded seismic data to constrain the planet's interior structure. The data reveal a layered crust, a mantle with a thick lithosphere, and a liquid iron-nickel core enriched in light elements, suggesting that Mars formed and evolved differently from Earth. See pages 388, 434, 438, and 443.
Illustration: C. Bickel/Science; Data: InSight Mars SEIS Data Service (2019)
