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April 27, 2021
- Socioeconomic status determines COVID-19 incidence and related mortality in Santiago, Chile
  
  By Gonzalo E. Mena, Pamela P. Martinez, Ayesha S. Mahmud, Pablo A. Marquet, Caroline O. Buckee, Mauricio Santillana
  
  Published Online27 Apr 2021 Open Access
  
  DOI: 10.1126/science.abg5298
  
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- Noncanonical crRNAs derived from host transcripts enable multiplexable RNA detection by Cas9
  
  By Chunlei Jiao, Sahil Sharma, Gaurav Dugar, Natalia L. Peeck, Thorsten Bischler, Franziska Wimmer, Yanying Yu, Lars Barquist, Christoph Schoen, Oliver Kurzai, Cynthia M. Sharma, Chase L. Beisel
  
  Published Online27 Apr 2021 Open Access
  
  DOI: 10.1126/science.abe7106
  
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April 23, 2021
- Resurgence of SARS-CoV-2: detection by community viral surveillance
  
  By Steven Riley, Kylie E. C. Ainslie, Oliver Eales, Caroline E. Walters, Haowei Wang, Christina Atchison, Claudio Fronterre, Peter J. Diggle, Deborah Ashby, Christl A. Donnelly, Graham Cooke, Wendy Barclay, Helen Ward, Ara Darzi, Paul Elliott
  
  Published Online23 Apr 2021 Open Access
  
  DOI: 10.1126/science.abf0874
  
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April 22, 2021
- Radiation-related genomic profile of papillary thyroid cancer after the Chernobyl accident
  
  By Lindsay M. Morton, Danielle M. Karyadi, Chip Stewart, Tetiana I. Bogdanova, Eric T. Dawson, Mia K. Steinberg, Jieqiong Dai, Stephen W. Hartley, Sara J. Schonfeld, Joshua N. Sampson, Yosi Maruvka, Vidushi Kapoor, Dale A. Ramsden, Juan Carvajal-Garcia, Charles M. Perou, Joel S. Parker, Marko Krznaric, Meredith Yeager, Joseph F. Boland, Amy Hutchinson, Belynda D. Hicks, Casey L. Dagnall, Julie M. Gastier-Foster, Jay Bowen, Olivia Lee, Mitchell J. Machiela, Elizabeth K. Cahoon, Alina V. Brenner, Kiyohiko Mabuchi, Vladimir Drozdovitch, Sergii Masiuk, Mykola Chepurny, Liudmyla Yu. Zurnadzhy, Maureen Hatch, Amy Berrington de Gonzalez, Gerry A. Thomas, Mykola D. Tronko, Gad Getz, Stephen J. Chanock
  
  Published Online22 Apr 2021 Full AccessRestricted Access
  
  DOI: 10.1126/science.abg2538
  
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- Mitochondrial NADP(H) generation is essential for proline biosynthesis
  
  By Jiajun Zhu, Simon Schwörer, Mirela Berisa, Yeon Ju Kyung, Keun Woo Ryu, Junmei Yi, Xuejun Jiang, Justin R. Cross, Craig B. Thompson
  
  Published Online22 Apr 2021 Full AccessRestricted Access
  
  DOI: 10.1126/science.abd5491
  
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- Lack of transgenerational effects of ionizing radiation exposure from the Chernobyl accident
  
  By Meredith Yeager, Mitchell J. Machiela, Prachi Kothiyal, Michael Dean, Clara Bodelon, Shalabh Suman, Mingyi Wang, Lisa Mirabello, Chase W. Nelson, Weiyin Zhou, Cameron Palmer, Bari Ballew, Leandro M. Colli, Neal D. Freedman, Casey Dagnall, Amy Hutchinson, Vibha Vij, Yosi Maruvka, Maureen Hatch, Iryna Illienko, Yuri Belayev, Nori Nakamura, Vadim Chumak, Elena Bakhanova, David Belyi, Victor Kryuchkov, Ivan Golovanov, Natalia Gudzenko, Elizabeth K. Cahoon, Paul Albert, Vladimir Drozdovitch, Mark P. Little, Kiyohiko Mabuchi, Chip Stewart, Gad Getz, Dimitry Bazyka, Amy Berrington de Gonzalez, Stephen J. Chanock
  
  Published Online22 Apr 2021 Full AccessRestricted Access
  
  DOI: 10.1126/science.abg2365
  
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- Nicotinamide mononucleotide increases muscle insulin sensitivity in prediabetic women
  
  By Mihoko Yoshino, Jun Yoshino, Brandon D. Kayser, Gary Patti, Michael P. Franczyk, Kathryn F. Mills, Miriam Sindelar, Terri Pietka, Bruce W. Patterson, Shin-Ichiro Imai, Samuel Klein
  
  Published Online22 Apr 2021 Full AccessRestricted Access
  
  DOI: 10.1126/science.abe9985
  
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April 15, 2021
- Structure reveals the activation mechanism of the MC4 receptor to initiate satiation signaling
  
  By Hadar Israeli, Oksana Degtjarik, Fabrizio Fierro, Vidicha Chunilal, Amandeep Kaur Gill, Nicolas J. Roth, Joaquin Botta, Vadivel Prabahar, Yoav Peleg, Li F. Chan, Danny Ben-Zvi, Peter J. McCormick, Masha Y. Niv, Moran Shalev-Benami
  
  Published Online15 Apr 2021 Full AccessRestricted Access
  
  DOI: 10.1126/science.abf7958
  
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- Reversible oxygen migration and phase transitions in hafnia-based ferroelectric devices
  
  By Pavan Nukala, Majid Ahmadi, Yingfen Wei, Sytze de Graaf, Evgenios Stylianidis, Tuhin Chakrabortty, Sylvia Matzen, Henny W. Zandbergen, Alexander Björling, Dan Mannix, Dina Carbone, Bart Kooi, Beatriz Noheda
  
  Published Online15 Apr 2021 Full AccessRestricted Access
  
  DOI: 10.1126/science.abf3789
  
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- Parity-preserving and magnetic field–resilient superconductivity in InSb nanowires with Sn shells
  
  By M. Pendharkar, B. Zhang, H. Wu, A. Zarassi, P. Zhang, C. P. Dempsey, J. S. Lee, S. D. Harrington, G. Badawy, S. Gazibegovic, R. L. M. Op het Veld, M. Rossi, J. Jung, A.-H. Chen, M. A. Verheijen, M. Hocevar, E. P. A. M. Bakkers, C. J. Palmstrøm, S. M. Frolov
  
  Published Online15 Apr 2021 Full AccessRestricted Access
  
  DOI: 10.1126/science.aba5211
  
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- Unearthing Neanderthal population history using nuclear and mitochondrial DNA from cave sediments
  
  By Benjamin Vernot, Elena I. Zavala, Asier Gómez-Olivencia, Zenobia Jacobs, Viviane Slon, Fabrizio Mafessoni, Frédéric Romagné, Alice Pearson, Martin Petr, Nohemi Sala, Adrián Pablos, Arantza Aranburu, José María Bermúdez de Castro, Eudald Carbonell, Bo Li, Maciej T. Krajcarz, Andrey I. Krivoshapkin, Kseniya A. Kolobova, Maxim B. Kozlikin, Michael V. Shunkov, Anatoly P. Derevianko, Bence Viola, Steffi Grote, Elena Essel, David López Herráez, Sarah Nagel, Birgit Nickel, Julia Richter, Anna Schmidt, Benjamin Peter, Janet Kelso, Richard G. Roberts, Juan-Luis Arsuaga, Matthias Meyer
  
  Published Online15 Apr 2021 Full AccessRestricted Access
  
  DOI: 10.1126/science.abf1667
  
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April 14, 2021
- Spatiotemporal pattern of COVID-19 spread in Brazil
  
  By Marcia C. Castro, Sun Kim, Lorena Barberia, Ana Freitas Ribeiro, Susie Gurzenda, Karina Braga Ribeiro, Erin Abbott, Jeffrey Blossom, Beatriz Rache, Burton H. Singer
  
  Published Online14 Apr 2021 Open Access
  
  DOI: 10.1126/science.abh1558
  
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- Genomics and epidemiology of the P.1 SARS-CoV-2 lineage in Manaus, Brazil
  
  By Nuno R. Faria, Thomas A. Mellan, Charles Whittaker, Ingra M. Claro, Darlan da S. Candido, Swapnil Mishra, Myuki A. E. Crispim, Flavia C. S. Sales, Iwona Hawryluk, John T. McCrone, Ruben J. G. Hulswit, Lucas A. M. Franco, Mariana S. Ramundo, Jaqueline G. de Jesus, Pamela S. Andrade, Thais M. Coletti, Giulia M. Ferreira, Camila A. M. Silva, Erika R. Manuli, Rafael H. M. Pereira, Pedro S. Peixoto, Moritz U. G. Kraemer, Nelson Gaburo Jr, Cecilia da C. Camilo, Henrique Hoeltgebaum, William M. Souza, Esmenia C. Rocha, Leandro M. de Souza, Mariana C. de Pinho, Leonardo J. T Araujo, Frederico S. V. Malta, Aline B. de Lima, Joice do P. Silva, Danielle A. G. Zauli, Alessandro C. de S. Ferreira, Ricardo P Schnekenberg, Daniel J. Laydon, Patrick G. T. Walker, Hannah M. Schlüter, Ana L. P. dos Santos, Maria S. Vidal, Valentina S. Del Caro, Rosinaldo M. F. Filho, Helem M. dos Santos, Renato S. Aguiar, José L. Proença-Modena, Bruce Nelson, James A. Hay, Mélodie Monod, Xenia Miscouridou, Helen Coupland, Raphael Sonabend, Michaela Vollmer, Axel Gandy, Carlos A. Prete Jr., Vitor H. Nascimento, Marc A. Suchard, Thomas A. Bowden, Sergei L. K. Pond, Chieh-Hsi Wu, Oliver Ratmann, Neil M. Ferguson, Christopher Dye, Nick J. Loman, Philippe Lemey, Andrew Rambaut, Nelson A. Fraiji, Maria do P. S. S. Carvalho, Oliver G. Pybus, Seth Flaxman, Samir Bhatt, Ester C. Sabino
  
  Published Online14 Apr 2021 Full AccessRestricted Access
  
  DOI: 10.1126/science.abh2644
  
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April 12, 2021
- Shared B cell memory to coronaviruses and other pathogens varies in human age groups and tissues
  
  By Fan Yang, Sandra C. A. Nielsen, Ramona A. Hoh, Katharina Röltgen, Oliver Fabian Wirz, Emily Haraguchi, Grace H. Jean, Ji-Yeun Lee, Tho D. Pham, Katherine J. L. Jackson, Krishna M. Roskin, Yi Liu, Khoa Nguyen, Robert S. Ohgami, Eleanor M. Osborne, Kari C. Nadeau, Claus U. Niemann, Julie Parsonnet, Scott D. Boyd
  
  Published Online12 Apr 2021 Open Access
  
  DOI: 10.1126/science.abf6648
  
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April 02, 2021
- X-ray screening identifies active site and allosteric inhibitors of SARS-CoV-2 main protease
  
  By Sebastian Günther, Patrick Y. A. Reinke, Yaiza Fernández-García, Julia Lieske, Thomas J. Lane, Helen M. Ginn, Faisal H. M. Koua, Christiane Ehrt, Wiebke Ewert, Dominik Oberthuer, Oleksandr Yefanov, Susanne Meier, Kristina Lorenzen, Boris Krichel, Janine-Denise Kopicki, Luca Gelisio, Wolfgang Brehm, Ilona Dunkel, Brandon Seychell, Henry Gieseler, Brenna Norton-Baker, Beatriz Escudero-Pérez, Martin Domaracky, Sofiane Saouane, Alexandra Tolstikova, Thomas A. White, Anna Hänle, Michael Groessler, Holger Fleckenstein, Fabian Trost, Marina Galchenkova, Yaroslav Gevorkov, Chufeng Li, Salah Awel, Ariana Peck, Miriam Barthelmess, Frank Schluenzen, Paulraj Lourdu Xavier, Nadine Werner, Hina Andaleeb, Najeeb Ullah, Sven Falke, Vasundara Srinivasan, Bruno Alves França, Martin Schwinzer, Hévila Brognaro, Cromarte Rogers, Diogo Melo, Joanna J. Zaitseva-Doyle, Juraj Knoska, Gisel E. Peña-Murillo, Aida Rahmani Mashhour, Vincent Hennicke, Pontus Fischer, Johanna Hakanpää, Jan Meyer, Philip Gribbon, Bernhard Ellinger, Maria Kuzikov, Markus Wolf, Andrea R. Beccari, Gleb Bourenkov, David von Stetten, Guillaume Pompidor, Isabel Bento, Saravanan Panneerselvam, Ivars Karpics, Thomas R. Schneider, Maria Marta Garcia-Alai, Stephan Niebling, Christian Günther, Christina Schmidt, Robin Schubert, Huijong Han, Juliane Boger, Diana C. F. Monteiro, Linlin Zhang, Xinyuanyuan Sun, Jonathan Pletzer-Zelgert, Jan Wollenhaupt, Christian G. Feiler, Manfred S. Weiss, Eike-Christian Schulz, Pedram Mehrabi, Katarina Karničar, Aleksandra Usenik, Jure Loboda, Henning Tidow, Ashwin Chari, Rolf Hilgenfeld, Charlotte Uetrecht, Russell Cox, Andrea Zaliani, Tobias Beck, Matthias Rarey, Stephan Günther, Dusan Turk, Winfried Hinrichs, Henry N. Chapman, Arwen R. Pearson, Christian Betzel, Alke Meents
  
  Published Online02 Apr 2021 Open Access
  
  DOI: 10.1126/science.abf7945
  
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April 01, 2021
- Structural insights into preinitiation complex assembly on core promoters
  
  By Xizi Chen, Yilun Qi, Zihan Wu, Xinxin Wang, Jiabei Li, Dan Zhao, Haifeng Hou, Yan Li, Zishuo Yu, Weida Liu, Mo Wang, Yulei Ren, Ze Li, Huirong Yang, Yanhui Xu
  
  Published Online01 Apr 2021 Full AccessRestricted Access
  
  DOI: 10.1126/science.aba8490
  
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March 25, 2021
- mRNA vaccination boosts cross-variant neutralizing antibodies elicited by SARS-CoV-2 infection
  
  By Leonidas Stamatatos, Julie Czartoski, Yu-Hsin Wan, Leah J. Homad, Vanessa Rubin, Hayley Glantz, Moni Neradilek, Emilie Seydoux, Madeleine F. Jennewein, Anna J. MacCamy, Junli Feng, Gregory Mize, Stephen C. De Rosa, Andrés Finzi, Maria P. Lemos, Kristen W. Cohen, Zoe Moodie, M. Juliana McElrath, Andrew T. McGuire
  
  Published Online25 Mar 2021 Open Access
  
  DOI: 10.1126/science.abg9175
  
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- Modulation of MHC-E transport by viral decoy ligands is required for RhCMV/SIV vaccine efficacy
  
  By Marieke Verweij, Scott G. Hansen, Ravi Iyer, Nessy John, Daniel Malouli, David Morrow, Isabel Scholz, Jennie Womack, Shaheed Abdulhaqq, Roxanne M. Gilbride, Colette M. Hughes, Abigail B. Ventura, Julia C. Ford, Andrea N. Selseth, Kelli Oswald, Rebecca Shoemaker, Brian Berkemeier, William J. Bosche, Michael Hull, Jason Shao, Jonah B. Sacha, Michael K. Axthelm, Paul T. Edlefsen, Jeffrey D. Lifson, Louis J. Picker, Klaus Früh
  
  Published Online25 Mar 2021 Full AccessRestricted Access
  
  DOI: 10.1126/science.abe9233
  
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March 23, 2021
- The impact of population-wide rapid antigen testing on SARS-CoV-2 prevalence in Slovakia
  
  By Martin Pavelka, Kevin Van-Zandvoort, Sam Abbott, Katharine Sherratt, Marek Majdan, CMMID COVID-19 working group, Inštitút Zdravotných Analýz, Pavol Jarčuška, Marek Krajčí, Stefan Flasche, Sebastian Funk
  
  Published Online23 Mar 2021 Open Access
  
  DOI: 10.1126/science.abf9648
  
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March 16, 2021
- Structural impact on SARS-CoV-2 spike protein by D614G substitution
  
  By Jun Zhang, Yongfei Cai, Tianshu Xiao, Jianming Lu, Hanqin Peng, Sarah M. Sterling, Richard M. Walsh Jr., Sophia Rits-Volloch, Haisun Zhu, Alec N. Woosley, Wei Yang, Piotr Sliz, Bing Chen
  
  Published Online16 Mar 2021 Open Access
  
  DOI: 10.1126/science.abf2303
  
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