Supporting Online Material

The Consensus Coding Sequences of Human Breast and Colorectal Cancers
Tobias Sjöblom, Siân Jones, Laura D. Wood, D. Williams Parsons, Jimmy Lin, Thomas Barber, Diana Mandelker, Rebecca J. Leary, Janine Ptak, Natalie Silliman, Steve Szabo, Phillip Buckhaults, Christopher Farrell, Paul Meeh, Sanford D. Markowitz, Joseph Willis, Dawn Dawson, James K. V. Willson, Adi F. Gazdar, James Hartigan, Leo Wu, Changsheng Liu, Giovanni Parmigiani, Ben Ho Park, Kurtis E. Bachman, Nickolas Papadopoulos, Bert Vogelstein, Kenneth W. Kinzler, Victor E. Velculescu

Supporting Online Material

This supplement contains:
Materials and Methods
Figs. S1 and S2
Tables S1 to S5

This file is in Adobe Acrobat PDF format.

Correction (24 October 2006): The authors have provided revised versions of Tables S5 and S6. In each table, one column is replaced by three more detailed columns "to clarify the number of observed mutations and make it easier for readers to identify genes of greatest interest for their further work." In each of the tables, the three new columns provide data on the number of tumors containing mutation in the discovery screen, the number of tumors containing mutation in the validation screen, and the number of mutations observed per Mb of sequence analyzed; these columns replace the column for estimated fraction of tumors containing mutation.

Revised Table S5

Revised Table S6

Tables S1 to S6. Data and supporting tables in Microsoft Word, Microsoft Excel, and PDF format (packaged as compressed archive, in *.zip format; users should download the compressed file to their machine and decompress the file on their local hard drive, using the instructions below):

  • Table S1 -- Primers used for PCR amplification and sequencing.
  • Table S2A and S2B -- Characteristics of breast and colorectal cancer samples.
  • Table S3 -- Distribution of mutations in individual cancers.
  • Table S4 -- Somatic mutations identified in breast and colorectal cancers.
  • Table S5 -- Breast CAN-genes.
  • Table S6 -- Colorectal CAN-genes. MB)

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