Supporting Online Material


The Genomic Landscapes of Human Breast and Colorectal Cancers
Laura D. Wood, D. Williams Parsons, Si�n Jones, Jimmy Lin, Tobias Sj�blom, Rebecca J. Leary, Dong Shen, Simina M. Boca, Thomas Barber, Janine Ptak, Natalie Silliman, Steve Szabo, Zoltan Dezso, Vadim Ustyanksky, Tatiana Nikolskaya, Yuri Nikolsky, Rachel Karchin, Paul A. Wilson, Joshua S. Kaminker, Zemin Zhang, Randal Croshaw, Joseph Willis, Dawn Dawson, Michail Shipitsin, James K. V. Willson, Saraswati Sukumar, Kornelia Polyak, Ben Ho Park, Charit L. Pethiyagoda, P. V. Krishna Pant, Dennis G. Ballinger, Andrew B. Sparks, James Hartigan, Douglas R. Smith, Erick Suh, Nickolas Papadopoulos, Phillip Buckhaults, Sanford D. Markowitz, Giovanni Parmigiani, Kenneth W. Kinzler, Victor E. Velculescu, Bert Vogelstein

Supporting Online Material

This supplement contains:
Materials and Methods
Fig. S1
References

This file is in Adobe Acrobat PDF format.

Other Supporting Online Material for this manuscript includes the following:
(available at www.sciencemag.org/cgi/content/full/1145720/DC1)
Tables S1 to S6
Statistical analysis package

Tables S1 to S6. Supporting tables, in Microsoft Excel and tab-delimited ASCII format; brief descriptions appear in main SOM PDF file. Files are packaged as a compressed archive, in *.zip format; users should download the compressed file to their machine and decompress the file on their local hard drive, using the instructions below.

Statistical analysis package. Statistical software codes, in the R programming language, for analyzing cancer mutations, along with data used in analysis presented. Files are packaged as a compressed archive, in *.zip format, for Windows and Macintosh users, and as gzipped tarfile for Unix and Linux environments; users should download the compressed file to their machine and decompress the file on their local hard drive, using the instructions below Questions about the software codes should be directed to the authors of the article.


Instructions for downloading and decompressing files:

*.zip archives --

  1. Create a temporary folder on your machine's hard drive.
  2. Save the compressed archive to the temporary folder you created, using the links above.
  3. Decompress the compressed file in the temporary folder using decompression software such as WinZip (Windows; www.winzip.com) or StuffIt Expander (Windows and Mac; www.stuffit.com).

gzipped tarfile --

  1. Save to your machine's hard drive.
  2. At the Un*x command line, try: gzcat [tarfilename].tar.gz | tar xvf -
  3. If you did not understand the preceding line, you should probably just use the *.zip file. (Gzipped tarfiles may also be extractable with extraction software such as Winzip.)

Excel files can be opened and viewed using Microsoft Excel, the spreadsheet module of the freely downloadable Open Office suite, or the freely downloadable Excel Viewer available from Microsoft. Text (ASCII) files can be opened and viewed in any text editor or word processing program. Questions about these files should be directed to the authors of the study.