Supplementary Materials

Mucus Enhances Gut Homeostasis and Oral Tolerance by Delivering Immunoregulatory Signals

Meimei Shan, Maurizio Gentile, John R. Yeiser, A. Cooper Walland, Victor U. Bornstein, Kang Chen, Bing He, Linda Cassis, Anna Bigas, Montserrat Cols, Laura Comerma, Bihui Huang, J. Magarian Blander, Huabao Xiong, Lloyd Mayer, Cecilia Berin, Leonard H. Augenlicht, Anna Velcich, Andrea Cerutti

Materials/Methods, Supporting Text, Tables, Figures, and/or References

Download Supplement
  • Materials and Methods
  • References (2937)
  • Acknowledgments
  • Figs. S1 to S22
  • Tables S1 to S8

Images, Video, and Other Other Media

Movie S1
Gut DC interacts with MUC2. Confocal microscopy and three-dimensional
animation of human gut tissue section stained for CD11c (green) and MUC2
(red) and counterstained with DAPI (blue). The movie was generated by
acquiring up to 53 x,y planes with 0.25 μm z spacing, three-dimensional
animation and volume enhancement of the green and red channels. Original
magnification, ×63; digital magnification ×5.5. One of three
experiments yielding similar results.
Movie S2
Gut DCs contain MUC2. Confocal microscopy and three-dimensional animation
of a human gut tissue section section stained for CD11c (green) and MUC2
(red) and counterstained with DAPI (blue). The movie was generated by
acquiring up to 47 x,y planes with 0.25 μm z spacing, three-dimensional
animation and volume enhancement of the green and red channels in
selected areas. Original magnification, ×63; digital magnification
×2.9. One of three experiments yielding similar results.