Supplementary Materials

Genomic correlates of response to CTLA4 blockade in metastatic melanoma

Eliezer M. Van Allen, Diana Miao, Bastian Schilling, Sachet A. Shukla, Christian Blank, Lisa Zimmer, Antje Sucker, Uwe Hillen, Marnix H. Geukes Foppen, Simone M. Goldinger, Jochen Utikal, Jessica C. Hassel, Benjamin Weide, Katharina C. Kaehler, Carmen Loquai, Peter Mohr, Ralf Gutzmer, Reinhard Dummer, Stacey Gabriel, Catherine J. Wu, Dirk Schadendorf, Levi A. Garraway

Materials/Methods, Supplementary Text, Tables, Figures, and/or References

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  • Materials and Methods
  • Figs. S1 to S4
  • Table S3
Table S1
Mutation list for all patients
Table S2
Detailed clinical and genome characteristics of individual patients
Table S4
Neoantigen list with HLA type and predicting MHC binding affinity for all patients
Table S5
Germline mutations in HLA class I
Correction (13 November 2015): An independent group of investigators noticed a small number of missing data entries in Table S4 concerning neoantigen binding affinities in one patient (Pat110 in the Report). Correcting the neoantigen calls in this case does not alter the results or conclusions of this investigation. Figure S1 and Tables S1, S2, S3, and S4 in the supplementary materials have been updated to reflect this change.
The original version is accessible here.
Correction (13 April 2016): It has come to Science's attention that the version of Table S4 posted on our website from 10 September 2015 through 13 November 2015 was not the final version intended for publication by the authors. Table S4 had undergone substantial revision during the peer-review process, including optimization of the neoantigen calling algorithm. Regrettably, the unrevised version of Table S4, which had been uploaded with the initial paper submission, was inadvertently posted upon publication. An Erratum pertaining to the version of Table S4 intended for publication-and unrelated to this posting error-was published on 13 November 2015. The link to the final, corrected version of Table S4 has been available on Science's website as of 13 November 2015 and can also be found here.