Supplementary Materials

The maternal microbiota drives early postnatal innate immune development

Mercedes Gomez de Ag├╝ero, Stephanie C. Ganal-Vonarburg, Tobias Fuhrer, Sandra Rupp, Yasuhiro Uchimura, Hai Li, Anna Steinert, Mathias Heikenwalder, Siegfried Hapfelmeier, Uwe Sauer, Kathy D. McCoy, Andrew J. Macpherson

Materials/Methods, Supplementary Text, Tables, Figures, and/or References

Download Supplement
  • Materials and Methods
  • Figs. S1 to S21
  • Tables S1 to S5
  • References
  • Captions for Data Files S1 to S8
Data File S1
RNA sequencing data of whole small intestine from wildtype day 14 pups comparing the offspring from control or gestationally colonized dams.
Data File S2
RNA sequencing data of lower part of small intestine from wild-type day 14 pups comparing the offspring from control or gestationally colonized dams.
Data File S3
RNA sequencing data of lower part of small intestine from JH-/- d14 pups comparing the offspring from control or gestationally colonized dams.
Data File S4
Mass spectrometry data (log2 fold-change, p-values, annotations) from maternal milk of WT and JH-/- mice or offspring tissues, collected on postnatal day 1-3, comparing samples of gestationally 13C-HA107 colonized to untreated control groups.
Data File S5
Mass spectrometry data from serum fractions (#1-31) after gel filtration of serum collected 6h after 13C-HA107 gavage from WT (A_WT_13C; B_WT_13C; C_WT_13C) and antibody-deficient (D_JHKO_13C; E_JHKO_13C; F_JHKO_13C) mice.
Data File S6
RNA sequencing data of lower part of small intestine from wild-type d14 pups comparing the offspring after E. coli JM83 challenge from control or gestationally colonized dams.
Data File S7
RNA sequencing data of lower part of small intestine from wild-type d14 pups comparing the offspring after E. coli JM83 or PBS challenge from control dams.
Data File S8
RNA sequencing data of lower part of small intestine from wild-type d14 pups comparing the offspring after E. coli JM83 or PBS challenge from gestationally colonized dams.