Supplementary Materials

Mutational signatures associated with tobacco smoking in human cancer

Ludmil B. Alexandrov, Young Seok Ju, Kerstin Haase, Peter Van Loo, IƱigo Martincorena, Serena Nik-Zainal, Yasushi Totoki, Akihiro Fujimoto, Hidewaki Nakagawa, Tatsuhiro Shibata, Peter J. Campbell, Paolo Vineis, David H. Phillips, Michael R. Stratton

Materials/Methods, Supplementary Text, Tables, Figures, and/or References

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  • Materials and Methods
  • Supplementary Text
  • Figs. S1 to S10
  • Captions for Tables S1 to S6
  • References
Table S1
Table S1: Detailed information about each examined tobacco-associated cancer sample. Table S2: Comparison of features of tobacco smokers to the ones of lifelong non-smokers. Table S3: Relationships between mutational signatures and pack years smoked. Table S4: Individual CpGs with differential methylation in lung adenocarcinoma. Table S5: Individual CpGs with differential methylation in oral cancer. Table S6: Numerical patterns of mutational signatures associated with tobacco smoking.