Supplementary Materials

Transcriptome-wide isoform-level dysregulation in ASD, schizophrenia, and bipolar disorder

Michael J. Gandal, Pan Zhang, Evi Hadjimichael, Rebecca L. Walker, Chao Chen, Shuang Liu, Hyejung Won, Harm van Bakel, Merina Varghese, Yongjun Wang, Annie W. Shieh, Jillian Haney, Sepideh Parhami, Judson Belmont, Minsoo Kim, Patricia Moran Losada, Zenab Khan, Justyna Mleczko, Yan Xia, Rujia Dai, Daifeng Wang, Yucheng T. Yang, Min Xu, Kenneth Fish, Patrick R. Hof, Jonathan Warrell, Dominic Fitzgerald, Kevin White, Andrew E. Jaffe, PsychENCODE Consortium, Mette A. Peters, Mark Gerstein, Chunyu Liu, Lilia M. Iakoucheva, Dalila Pinto, Daniel H. Geschwind

Materials/Methods, Supplementary Text, Tables, Figures, and/or References

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  • Materials and Methods
  • Figs. S1 to S17
  • Captions for Tables S1 to S9
  • PsychENCODE Consortium Authors and Affiliations
  • References
Table S1
Differential gene and isoform expression summary statistics and DE enrichment analyses
Table S2
Annotation of neuropsychiatric ncRNAs ('NPncRNAs')
Table S3
Differential splicing summary statistics, annotation and disease overlaps
Table S4
TWAS and SMR summary statistics, PRS associations with gene and isoform expression
Table S5
Gene and isoform co-expression module annotation
Table S6
csuWGCNA network annotation and putative lncRNA-mRNA targets
Table S7
Switch isoform and microexon characterization
Table S8
Splicing and isoform validation primers and samples
Table S9
RNAscope - Tissue samples and RNA FISH probes