Supplementary Materials

A Kelch13-defined endocytosis pathway mediates artemisinin resistance in malaria parasites

Jakob Birnbaum, Sarah Scharf, Sabine Schmidt, Ernst Jonscher, Wieteke Anna Maria Hoeijmakers, Sven Flemming, Christa Geeke Toenhake, Marius Schmitt, Ricarda Sabitzki, Bärbel Bergmann, Ulrike Fröhlke, Paolo Mesén-Ramírez, Alexandra Blancke Soares, Hendrik Herrmann, Richárd Bártfai, Tobias Spielmann

Materials/Methods, Supplementary Text, Tables, Figures, and/or References

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  • Materials and Methods
  • Figs. S1 to S14
  • Caption for Table S1
  • Captions for Data S1 to S4
  • References
Table S1
Summary of findings in this study
Data S1
DiQ-BioID results for Kelch13, Eps15 and CHC. Proteins enriched in rapalog over control, ranked on average log2 normalized ratio from high to low. Sub-tables show DiQ-BioID results for each of the targets and all combined. Details indicated in the legend subtable.
Data S2
DiQ-BioID results without target. Proteins enriched in rapalog over control, ranked on average log2 normalized ratio from high to low. Details indicated in the legend sub-table.
Data S3
DiQ-BioID results for Kelch13. DIQ-BioID results of proteins significantly enriched (rapalog over control) with FDR<1% in at least 1 experiment of Kelch13 or Kelch13C570Y DIQ-BioID. The second sub-table includes all proteins identified in the combined analysis of Kelch13 (n=4) and Kelch13C580Y (n=2) DIQ-BioID experiments. Details indicated in the legend sub-table.
Data S4
Primers used in this study.