Supplementary Materials

Structural basis for membrane insertion by the human ER membrane protein complex

Tino Pleiner, Giovani Pinton Tomaleri, Kurt Januszyk, Alison J. Inglis, Masami Hazu, Rebecca M. Voorhees

Materials/Methods, Supplementary Text, Tables, Figures, and/or References

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  • Materials and Methods
  • Figs. S1 to S14
  • Tables S1 to S3
  • Captions for Movies S1 to S3
  • References
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Images, Video, and Other Media

Movie S1
Movie depicting the structure of the human EMC, highlighting the cryo-EM density map and model shown in Figure 1.
Movie S2
Movie highlighting the cryo-EM density for the dynamic transmembrane helices of EMC4, 7 and 10, which partially enclose the hydrophilic vestibule of the EMC.
Movie S3
Movie of the cryo-EM density map and atomic model of the EMC depicting the local thinning of the lipid bilayer by the complex.