Supplementary Materials

The coupling mechanism of mammalian respiratory complex I

Domen Kampjut and Leonid A. Sazanov

Materials/Methods, Supplementary Text, Tables, Figures, and/or References

Download Supplement
  • Supplementary Text
  • Figs. S1 to S11
  • Tables S1 to S7
  • Captions for Movies S1 and S2
  • References
MDAR Reproducibility Checklist

Images, Video, and Other Media

Movie S1
Opening and closing of complex I result in large scale reorganization of ND1 and ND6 subunits.
Movie S2
Quinone diffusion out of the cavity is aided by conformational changes of the 49 kDa, ND1 and PSST loops during opening and reduction of the complex.