Supplementary Materials
Network-based screen in iPSC-derived cells reveals therapeutic candidate for heart
valve disease
Christina V. Theodoris, Ping Zhou, Lei Liu, Yu Zhang, Tomohiro Nishino, Yu Huang, Aleksandra Kostina, Sanjeev S. Ranade, Casey A. Gifford, Vladimir Uspenskiy, Anna Malaschicheva, Sheng Ding, Deepak Srivastava
Materials/Methods, Supplementary Text, Tables, Figures, and/or References
- Download Supplement
- Materials and Methods
- Figs. S1 to S12
- Captions for Data S1 to S5
- References
- Data S1
- Targeted RNA-seq gene panel Gene transcripts measured in targeted RNA-seq experiments.
- Data S2
- Network-correcting molecule candidates identified by network-based small molecule screen Network-correcting molecule candidates identified by KNN and hierarchical clustering algorithms.
- Data S3
- Primary AV ECs Characteristics of patients from which primary AV ECs were derived.
- Data S4
- GO analysis of genes dysregulated in primary AV ECs GO analysis of genes dysregulated in primary cTAV and cBAV ECs by cluster.
- Data S5
- GO analysis of genes dysregulated in mouse AVs GO analysis of genes uniquely dysregulated in control-treated N1+/�/mTRG2 mice with AV disease (increased AV peak velocity, as opposed to N1+/�/mTRG2 mice with healthy AVs) compared to N1WT/mTRG2 mice.
- MDAR Reproducibility Checklist
