Supplementary Materials

Structural basis for target-site selection in RNA-guided DNA transposition systems

Jung-Un Park, Amy Tsai, Eshan Mehrotra, Michael T. Petassi, Shan-Chi Hsieh, Ailong Ke, Joseph E. Peters, Elizabeth H. Kellogg

Materials/Methods, Supplementary Text, Tables, Figures, and/or References

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  • Materials and Methods
  • Figs. S1 to S15
  • Tables S1 to S3
  • Captions for Movie S1 and S2
  • References
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Images, Video, and Other Media

Movie S1
3D variability analysis reveals the conformational changes in the ADP•AlF3 sample. We are able to visualize the structural changes between the 'closed' and the 'open' conformation within the ADP•AlF3 ensemble.
Movie S1
Summary of our proposed model (generated using Chimera-X(70) and Keynote), integrating the results obtained from the cryo-EM and biochemical data presented here.