PT  - JOURNAL ARTICLE
AU  - Wilt, Fred H.
TI  - Erythropoiesis in the Chick Embryo: The Role of Endoderm
AID  - 10.1126/science.147.3665.1588
DP  - 1965 Mar 26
TA  - Science
PG  - 1588--1590
VI  - 147
IP  - 3665
4099  - http://science.sciencemag.org/content/147/3665/1588.short
4100  - http://science.sciencemag.org/content/147/3665/1588.full
SO  - Science1965 Mar 26; 147
AB  - The endoderm can be separated from the ectomesoderm of the area vasculosa of the early chick embryo. The development of the separated germ layers in organ cultures shows that the endoderm is necessary for the normal formation of blood islands by mesodermal cells. In the absence of endoderm the mesodermal cells undergo erythropoiesis in dispersed groups of cells but do not form endothelium.