RT Journal Article
SR Electronic
T1 Erythropoiesis in the Chick Embryo: The Role of Endoderm
JF Science
JO Science
FD American Association for the Advancement of Science
SP 1588
OP 1590
DO 10.1126/science.147.3665.1588
VO 147
IS 3665
A1 Wilt, Fred H.
YR 1965
UL http://science.sciencemag.org/content/147/3665/1588.abstract
AB The endoderm can be separated from the ectomesoderm of the area vasculosa of the early chick embryo. The development of the separated germ layers in organ cultures shows that the endoderm is necessary for the normal formation of blood islands by mesodermal cells. In the absence of endoderm the mesodermal cells undergo erythropoiesis in dispersed groups of cells but do not form endothelium.