RT Journal Article
SR Electronic
T1 Release of Catecholamines and Specific Protein from Adrenal Glands
JF Science
JO Science
FD American Association for the Advancement of Science
SP 529
OP 531
DO 10.1126/science.154.3748.529
VO 154
IS 3748
A1 Kirshner, Norman
A1 Sage, Harvey J.
A1 Smith, W. James
A1 Kirshner, Annette G.
YR 1966
UL http://science.sciencemag.org/content/154/3748/529.abstract
AB Rabbit antiserums directed against a purified protein obtained from the catecholamine storage vesicles of the adrenal medulla of the cow were used to study the mechanism of secretion from the adrenal medulla. During secretion evoked by acetylcholine in isolated perfused adrenal glands, catecholamines and the specific intravesicular protein were released in relative amounts comparable to those present in the intact gland. Thus catecholamines are apparently released from the storage vesicles by a process resembling reverse pinocytosis.