PT - JOURNAL ARTICLE AU - Hilgard, Henry R. AU - Phillips, John H. TI - Sea Urchin Response to Foreign Substances AID - 10.1126/science.161.3847.1243 DP - 1968 Sep 20 TA - Science PG - 1243--1245 VI - 161 IP - 3847 4099 - http://science.sciencemag.org/content/161/3847/1243.short 4100 - http://science.sciencemag.org/content/161/3847/1243.full SO - Science1968 Sep 20; 161 AB - An assessment of the response of Strongylocentrotus purpuratus to substances injected into the coelom shows that (i) foreign molecules are cleared from the coelomic fluid more rapidly than native molecules, (ii) coelomocytes can respond selectively to albumins of human and bovine origin, and (iii) immunization attempts fail to elicit accelerated coelomocyte uptake or accelerated clear-with antigen.