RT Journal Article
SR Electronic
T1 Glycolipid and Mucopolysaccharide Abnormality in Fibroblasts of Fabry's Disease
JF Science
JO Science
FD American Association for the Advancement of Science
SP 1522
OP 1523
DO 10.1126/science.164.3887.1522
VO 164
IS 3887
A1 Matalon, Reuben
A1 Dorfman, Albert
A1 Dawson, Glyn
A1 Sweeley, Charles C.
YR 1969
UL http://science.sciencemag.org/content/164/3887/1522.abstract
AB Cultures of skin fiibroblasts from a patient with Fabry's disease showed an accumulation of the glycolipid, galactosyl-galactosyl-glucosyl ceramide. Such cells also showed metachromasia on staining with toluidine blue and a markedly elevated acid mucopolysaccharide content.