RT Journal Article
SR Electronic
T1 Hepatitis in Marmosets: Induction of Disease with Coded Specimens from a Human Volunteer Study
JF Science
JO Science
FD American Association for the Advancement of Science
SP 816
OP 817
DO 10.1126/science.165.3895.816
VO 165
IS 3895
A1 Holmes, Albert W.
A1 Wolfe, Lauren
A1 Rosenblate, Howard
A1 Deinhardt, Friedrich
YR 1969
UL http://science.sciencemag.org/content/165/3895/816.abstract
AB Marmosets inoculated with plasma from three early acute hepatitis patients developed hepatitis 30 to 40 days later. Other groups of marmosets receiving preinfection plasmas from the same patients showed no evidence of hepatitis in this experiment. It is, therefore, most probable that hepatitis in marmosets represented transmission of human disease rather than activation of latent "marmoset hepatitis."