PT - JOURNAL ARTICLE AU - Hooks, John AU - Gibbs, C. J. AU - Chopra, H. AU - Lewis, M. AU - Gajdusek, D. C. TI - Spontaneous Transformation of Human Brain Cells Grown in vitro and Description of Associated Virus Particles AID - 10.1126/science.176.4042.1420 DP - 1972 Jun 30 TA - Science PG - 1420--1422 VI - 176 IP - 4042 4099 - http://science.sciencemag.org/content/176/4042/1420.short 4100 - http://science.sciencemag.org/content/176/4042/1420.full SO - Science1972 Jun 30; 176 AB - A human brain cell culture grown in vitro has spontaneously transformed, as determined by morphology, growth characteristics, and karyotype analysis. Virus particles morphologically akin to oncogenic RNA viruses are present in the transformed cells, which are now in subculture 60.