PT - JOURNAL ARTICLE AU - Sassin, J. F. AU - Frantz, A. G. AU - Weitzman, E. D. AU - Kapen, S. TI - Human Prolactin: 24-Hour Pattern with Increased Release doring Sleep AID - 10.1126/science.177.4055.1205 DP - 1972 Sep 29 TA - Science PG - 1205--1207 VI - 177 IP - 4055 4099 - http://science.sciencemag.org/content/177/4055/1205.short 4100 - http://science.sciencemag.org/content/177/4055/1205.full SO - Science1972 Sep 29; 177 AB - Human prolactin was measured in plasma by radioimmunoassay at 20 minute intervals for a 24-hour period in each of six normal adults, whose sleep-wake cycles were monitored polygraphically. A marked diurnal variation in plasma concentrations was demonstrated, with highest values during sleep; periods of episodic release occurred throughout the 24 hours.