RT Journal Article
SR Electronic
T1 Primary bioassay of human tumor stem cells
JF Science
JO Science
FD American Association for the Advancement of Science
SP 461
OP 463
DO 10.1126/science.560061
VO 197
IS 4302
A1 Hamburger, AW
A1 Salmon, SE
YR 1977
UL http://science.sciencemag.org/content/197/4302/461.abstract
AB A simple method has been developed to support human tumor stem cell colony growth in soft agar. The technique appears suitable for culture of a variety of neoplasms of differing histopathology. Tumor stem cell colonies arising from different types of cancer have differing growth characteristics and colony morphology. This bioassay should be suitable for clinical studies of effects of anticancer drugs or irradiation on human tumor stem cells.