PT - JOURNAL ARTICLE AU - Moore, KW AU - Sher, BT AU - Sun, YH AU - Eakle, KA AU - Hood, L TI - DNA sequence of a gene encoding a BALB/c mouse Ld transplantation antigen AID - 10.1126/science.7058332 DP - 1982 Feb 05 TA - Science PG - 679--682 VI - 215 IP - 4533 4099 - http://science.sciencemag.org/content/215/4533/679.short 4100 - http://science.sciencemag.org/content/215/4533/679.full SO - Science1982 Feb 05; 215 AB - The sequence of a gene, denoted 27.5, encoding a transplantation antigen for the BALB/c mouse has been determined. Gene transfer studies and comparison of the translated sequence with the partial amino acid sequence of the Ld transplantation antigen establish that gene 27.5 encodes an Ld polypeptide. A comparison of the gene 27.5 sequence with several complementary DNA sequences suggests that the BALB/c mouse may contain a number of closely related L-like genes. Gene 27.5 has eight exons that correlate with the structural domains of the transplantation antigen.