PT - JOURNAL ARTICLE AU - Gupta, C AU - Yaffe, SJ AU - Shapiro, BH TI - Prenatal exposure to phenobarbital permanently decreases testosterone and causes reproductive dysfunction AID - 10.1126/science.7200262 DP - 1982 May 07 TA - Science PG - 640--642 VI - 216 IP - 4546 4099 - http://science.sciencemag.org/content/216/4546/640.short 4100 - http://science.sciencemag.org/content/216/4546/640.full SO - Science1982 May 07; 216 AB - Exposure of rats to phenobarbital during late prenatal development decreased the concentration of testosterone in plasma and the brain during the late fetal, early postnatal, pubertal, and adult periods, By decreasing the production of testosterone in the brain during the period of sexual differentiation, phenobarbital may lead to sexual dysfunction in later life.