RT Journal Article SR Electronic T1 Prenatal exposure to phenobarbital permanently decreases testosterone and causes reproductive dysfunction JF Science JO Science FD American Association for the Advancement of Science SP 640 OP 642 DO 10.1126/science.7200262 VO 216 IS 4546 A1 Gupta, C A1 Yaffe, SJ A1 Shapiro, BH YR 1982 UL http://science.sciencemag.org/content/216/4546/640.abstract AB Exposure of rats to phenobarbital during late prenatal development decreased the concentration of testosterone in plasma and the brain during the late fetal, early postnatal, pubertal, and adult periods, By decreasing the production of testosterone in the brain during the period of sexual differentiation, phenobarbital may lead to sexual dysfunction in later life.