RT Journal Article
SR Electronic
T1 Trends in Analytical Scale Separations
JF Science
JO Science
FD American Association for the Advancement of Science
SP 254
OP 261
DO 10.1126/science.226.4672.254
VO 226
IS 4672
A1 Jorgenson, James W.
YR 1984
UL http://science.sciencemag.org/content/226/4672/254.abstract
AB Although gas chromatography has been called a mature technology, advances are still being made in the development of faster columns as well as detectors which yield more information on solutes. In liquid chromatography short columns packed with 3-micrometer particles are already popular for fast analyses, while long narrow-bore columns are being developed for high-resolution separations. An increasing range of detection modes is enhancing the problem-solving capabilities of liquid chromatography. Electrophoresis continues to be of central importance to molecular biology. Computer-aided analysis and display of electropherogram patterns is helping researchers to better comprehend the wealth of data from two-dimensional electrophoresis. A new mode of two-dimensional electrophoresis is permitting separation of whole chromosomes containing as many as 3 million base pairs.