RT Journal Article SR Electronic T1 New methods of drug delivery JF Science JO Science FD American Association for the Advancement of Science SP 1527 OP 1533 DO 10.1126/science.2218494 VO 249 IS 4976 A1 Langer, R YR 1990 UL http://science.sciencemag.org/content/249/4976/1527.abstract AB Conventional forms of drug administration generally rely on pills, eye drops, ointments, and intravenous solutions. Recently, a number of novel drug delivery approaches have been developed. These approaches include drug modification by chemical means, drug entrapment in small vesicles that are injected into the bloodstream, and drug entrapment within pumps or polymeric materials that are placed in desired bodily compartments (for example, the eye or beneath the skin). These techniques have already led to delivery systems that improve human health, and continued research may revolutionize the way many drugs are delivered.