PT  - JOURNAL ARTICLE
AU  - Grant, MR
AU  - Godiard, L
AU  - Straube, E
AU  - Ashfield, T
AU  - Lewald, J
AU  - Sattler, A
AU  - Innes, RW
AU  - Dangl, JL
TI  - Structure of the Arabidopsis RPM1 gene enabling dual specificity disease resistance
AID  - 10.1126/science.7638602
DP  - 1995 Aug 11
TA  - Science
PG  - 843--846
VI  - 269
IP  - 5225
4099  - http://science.sciencemag.org/content/269/5225/843.short
4100  - http://science.sciencemag.org/content/269/5225/843.full
SO  - Science1995 Aug 11; 269
AB  - Plants can recognize pathogens through the action of disease resistance (R) genes, which confer resistance to pathogens expressing unique corresponding avirulence (avr) genes. The molecular basis of this gene-for-gene specificity is unknown. The Arabidopsis thaliana RPM1 gene enables dual specificity to pathogens expressing either of two unrelated Pseudomonas syringae avr genes. Despite this function, RPM1 encodes a protein sharing molecular features with recently described single-specificity R genes. Surprisingly, RPM1 is lacking from naturally occurring, disease-susceptible Arabidopsis accessions.