PT  - JOURNAL ARTICLE
AU  - Song, Wen-Yuan
AU  - Wang, Guo-Liang
AU  - Chen, Li-Li
AU  - Kim, Han-Suk
AU  - Pi, Li-Ya
AU  - Holsten, Tom
AU  - Gardner, J.
AU  - Wang, Bei
AU  - Zhai, Wen-Xue
AU  - Zhu, Li-Huang
AU  - Fauquet, Claude
AU  - Ronald, Pamela
TI  - A Receptor Kinase-Like Protein Encoded by the Rice Disease Resistance Gene, <em>Xa21</em>
AID  - 10.1126/science.270.5243.1804
DP  - 1995 Dec 15
TA  - Science
PG  - 1804--1806
VI  - 270
IP  - 5243
4099  - http://science.sciencemag.org/content/270/5243/1804.short
4100  - http://science.sciencemag.org/content/270/5243/1804.full
SO  - Science1995 Dec 15; 270
AB  - The rice Xa21 gene, which confers resistance to Xanthomonas oryzae pv. oryzae race 6, was isolated by positional cloning. Fifty transgenic rice plants carrying the cloned Xa21 gene display high levels of resistance to the pathogen. The sequence of the predicted protein, which carries both a leucine-rich repeat motif and a serine-threonine kinase-like domain, suggests a role in cell surface recognition of a pathogen ligand and subsequent activation of an intracellular defense response. Characterization of Xa21 should facilitate understanding of plant disease resistance and lead to engineered resistance in rice.