PT  - JOURNAL ARTICLE
AU  - Cockett, Noelle E.
AU  - Jackson, Sam P.
AU  - Shay, Tracy L.
AU  - Farnir, Frédéric
AU  - Berghmans, Stéphane
AU  - Snowder, Gary D.
AU  - Nielsen, Dahlia M.
AU  - Georges, Michel
TI  - Polar Overdominance at the Ovine <strong><em>callipyge</em></strong> Locus
AID  - 10.1126/science.273.5272.236
DP  - 1996 Jul 12
TA  - Science
PG  - 236--238
VI  - 273
IP  - 5272
4099  - http://science.sciencemag.org/content/273/5272/236.short
4100  - http://science.sciencemag.org/content/273/5272/236.full
SO  - Science1996 Jul 12; 273
AB  - An inheritable muscular hypertrophy was recently described in sheep and shown to be determined by the callipyge gene mapped to ovine chromosome 18. Here, the callipyge phenotype was found to be characterized by a nonmendelian inheritance pattern, referred to as polar overdominance, where only heterozygous individuals having inherited the callipyge mutation from their sire express the phenotype. The possible role of parental imprinting in the determinism of polar overdominance is envisaged.