RT Journal Article
SR Electronic
T1 Polar Overdominance at the Ovine <strong><em>callipyge</em></strong> Locus
JF Science
JO Science
FD American Association for the Advancement of Science
SP 236
OP 238
DO 10.1126/science.273.5272.236
VO 273
IS 5272
A1 Cockett, Noelle E.
A1 Jackson, Sam P.
A1 Shay, Tracy L.
A1 Farnir, Frédéric
A1 Berghmans, Stéphane
A1 Snowder, Gary D.
A1 Nielsen, Dahlia M.
A1 Georges, Michel
YR 1996
UL http://science.sciencemag.org/content/273/5272/236.abstract
AB An inheritable muscular hypertrophy was recently described in sheep and shown to be determined by the callipyge gene mapped to ovine chromosome 18. Here, the callipyge phenotype was found to be characterized by a nonmendelian inheritance pattern, referred to as polar overdominance, where only heterozygous individuals having inherited the callipyge mutation from their sire express the phenotype. The possible role of parental imprinting in the determinism of polar overdominance is envisaged.