PT - JOURNAL ARTICLE AU - Carter, Cameron S. AU - Braver, Todd S. AU - Barch, Deanna M. AU - Botvinick, Matthew M. AU - Noll, Douglas AU - Cohen, Jonathan D. TI - Anterior Cingulate Cortex, Error Detection, and the Online Monitoring of Performance AID - 10.1126/science.280.5364.747 DP - 1998 May 01 TA - Science PG - 747--749 VI - 280 IP - 5364 4099 - http://science.sciencemag.org/content/280/5364/747.short 4100 - http://science.sciencemag.org/content/280/5364/747.full SO - Science1998 May 01; 280 AB - An unresolved question in neuroscience and psychology is how the brain monitors performance to regulate behavior. It has been proposed that the anterior cingulate cortex (ACC), on the medial surface of the frontal lobe, contributes to performance monitoring by detecting errors. In this study, event-related functional magnetic resonance imaging was used to examine ACC function. Results confirm that this region shows activity during erroneous responses. However, activity was also observed in the same region during correct responses under conditions of increased response competition. This suggests that the ACC detects conditions under which errors are likely to occur rather than errors themselves.