RT Journal Article
SR Electronic
T1 <em>Arabidopsis</em> Transcription Factors: Genome-Wide Comparative Analysis Among Eukaryotes
JF Science
JO Science
FD American Association for the Advancement of Science
SP 2105
OP 2110
DO 10.1126/science.290.5499.2105
VO 290
IS 5499
A1 Riechmann, J. L.
A1 Heard, J.
A1 Martin, G.
A1 Reuber, L.
A1 Jiang , C.-Z.
A1 Keddie, J.
A1 Adam, L.
A1 Pineda, O.
A1 Ratcliffe, O. J.
A1 Samaha, R. R.
A1 Creelman, R.
A1 Pilgrim, M.
A1 Broun, P.
A1 Zhang, J. Z.
A1 Ghandehari, D.
A1 Sherman, B. K.
A1 -L. Yu, G.
YR 2000
UL http://science.sciencemag.org/content/290/5499/2105.abstract
AB The completion of the Arabidopsis thaliana genome sequence allows a comparative analysis of transcriptional regulators across the three eukaryotic kingdoms. Arabidopsis dedicates over 5% of its genome to code for more than 1500 transcription factors, about 45% of which are from families specific to plants.Arabidopsis transcription factors that belong to families common to all eukaryotes do not share significant similarity with those of the other kingdoms beyond the conserved DNA binding domains, many of which have been arranged in combinations specific to each lineage. The genome-wide comparison reveals the evolutionary generation of diversity in the regulation of transcription.