RT Journal Article
SR Electronic
T1 Control of Stomatal Distribution on the <em>Arabidopsis</em> Leaf Surface
JF Science
JO Science
FD American Association for the Advancement of Science
SP 1697
OP 1700
DO 10.1126/science.1069596
VO 296
IS 5573
A1 Nadeau, Jeanette A.
A1 Sack, Fred D.
YR 2002
UL http://science.sciencemag.org/content/296/5573/1697.abstract
AB Stomata regulate gas exchange and are distributed across the leaf epidermis with characteristic spacing. Arabidopsisstomata are produced by asymmetric cell divisions. Mutations in the gene TOO MANY MOUTHS (TMM) disrupt patterning by randomizing the plane of formative asymmetric divisions and by permitting ectopic divisions. TMM encodes a leucine-rich repeat–containing receptor-like protein expressed in proliferative postprotodermal cells. TMM appears to function in a position-dependent signaling pathway that controls the plane of patterning divisions as well as the balance between stem cell renewal and differentiation in stomatal and epidermal development.