RT Journal Article
SR Electronic
T1 Lateralized Cognitive Processes and Lateralized Task Control in the Human Brain
JF Science
JO Science
FD American Association for the Advancement of Science
SP 384
OP 386
DO 10.1126/science.1086025
VO 301
IS 5631
A1 Stephan, Klaas E.
A1 Marshall, John C.
A1 Friston, Karl J.
A1 Rowe, James B.
A1 Ritzl, Afra
A1 Zilles, Karl
A1 Fink, Gereon R.
YR 2003
UL http://science.sciencemag.org/content/301/5631/384.abstract
AB The principles underlying human hemispheric specialization are poorly understood. We used functional magnetic resonance imaging of letter and visuospatial decision tasks with identical word stimuli to address two unresolved problems. First, hemispheric specialization depended on the nature of the task rather than on the nature of the stimulus. Second, analysis of frontal candidate regions for cognitive control showed increased coupling between left anterior cingulate cortex (ACC) and left inferior frontal gyrus during letter decisions, whereas right ACC showed enhanced coupling with right parietal areas during visuospatial decisions. Cognitive control is thus localized in the same hemisphere as task execution.