PT - JOURNAL ARTICLE AU - Buzsáki, György AU - Draguhn, Andreas TI - Neuronal Oscillations in Cortical Networks AID - 10.1126/science.1099745 DP - 2004 Jun 25 TA - Science PG - 1926--1929 VI - 304 IP - 5679 4099 - http://science.sciencemag.org/content/304/5679/1926.short 4100 - http://science.sciencemag.org/content/304/5679/1926.full SO - Science2004 Jun 25; 304 AB - Clocks tick, bridges and skyscrapers vibrate, neuronal networks oscillate. Are neuronal oscillations an inevitable by-product, similar to bridge vibrations, or an essential part of the brain's design? Mammalian cortical neurons form behavior-dependent oscillating networks of various sizes, which span five orders of magnitude in frequency. These oscillations are phylogenetically preserved, suggesting that they are functionally relevant. Recent findings indicate that network oscillations bias input selection, temporally link neurons into assemblies, and facilitate synaptic plasticity, mechanisms that cooperatively support temporal representation and long-term consolidation of information.