RT Journal Article
SR Electronic
T1 Plant Cuticular Lipid Export Requires an ABC Transporter
JF Science
JO Science
FD American Association for the Advancement of Science
SP 702
OP 704
DO 10.1126/science.1102331
VO 306
IS 5696
A1 Pighin, Jamie A.
A1 Zheng, Huanquan
A1 Balakshin, Laura J.
A1 Goodman, Ian P.
A1 Western, Tamara L.
A1 Jetter, Reinhard
A1 Kunst, Ljerka
A1 Samuels, A. Lacey
YR 2004
UL http://science.sciencemag.org/content/306/5696/702.abstract
AB A waxy protective cuticle coats all primary aerial plant tissues. Its synthesis requires extensive export of lipids from epidermal cells to the plant surface. Arabidopsis cer5 mutants had reduced stem cuticular wax loads and accumulated sheetlike inclusions in the cytoplasm of wax-secreting cells. These inclusions represented abnormal deposits of cuticular wax and resembled inclusions found in a human disorder caused by a defective peroxisomal adenosine triphosphate binding cassette (ABC) transporter. We found that the CER5 gene encodes an ABC transporter localized in the plasma membrane of epidermal cells and conclude that it is required for wax export to the cuticle.